Intra-cellular traffic: bio-molecular motors on filamentary tracks
نویسندگان
چکیده
Debashish Chowdhury†,1 Aakash Basu, Ashok Garai, Philip Greulich, Katsuhiro Nishinari, Andreas Schadschneider, and Tripti Tripathi Department of Physics, Indian Institute of Technology, Kanpur 208016, India Institute for Theoretical Physics, University of Cologne, D-50937 Köln, Germany 3 Department of Aeronautics and Astronautics, Faculty of Engineering, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-8656, Japan (Dated: February 2, 2008)
منابع مشابه
Collective effects in intra-cellular molecular motor transport: coordination, cooperation and competetion
Molecular motors do not work in isolation in-vivo. We highlight some of the coordinations, cooperations and competitions that determine the collective properties of molecular motors in eukaryotic cells. In the context of traffic-like movement of motors on a track, we emphasize the importance of single-motor bio-chemical cycle and enzymatic activity on their collective spatio-temporal organisati...
متن کاملComputational modelling of the collective stochastic motion of Kinesin nano motors
We have developed a two dimensional stochastic molecular dynamics model for the description of intra cellular collective motion of bio motors, in particular Kinesins, on a microtubular track. The model is capable or reproducing the hand-over-hand mechanism of the directed motion along the microtubule. The model gives the average directed velocity and the current of Kinesins along the microtubul...
متن کاملFrom aggressive driving to molecular motor traffic
Motivated by recent experimental results for the step sizes of dynein motor proteins, we develope a cellular automata model for intra-cellular traffic of dynein motors incorporating special features of the hindrance-dependent step size of the individual motors. We begin by investigating the properties of the aggressive driving model (ADM), a simple cellular automata-based model of vehicular tra...
متن کاملIntracellular Transport: Force Controls Motor Switching at Filament Junctions
How does cellular traffic switch direction on microtubules, or switch back and forth between microtubule- and actin-based tracks? A pair of recent studies mimics the layout of motors and tracks within the cell to provide intriguing answers to these questions.
متن کاملSelf-organization versus watchmaker: molecular motors and protein translocation.
Generation of directional movement at the molecular scale is a phenomenon crucial for biological organization and dynamics. It is traditionally described in mechanistic terms, in consistency with the conventional machine-like image of the cell. The designated and highly specialized protein machines and molecular motors are presumed to bring about most of cellular motion. A review of experimenta...
متن کامل